In Vitro Research Without sacrificing relevance
In vitro research has many advantages over in vivo research, such as (1) tight control of chemical and physical environment, (2) it is cheaper, and (3) faster, and (4) fewer animals are needed. However, isolated and cultivated primary cells to differ from the corresponding cell type in an organism, limiting the value of in vitro data to predict in vivo behavior. A major reason for this divergence is that in vitro experiments do not replicate the mechanical and electrical environment of cells in an organism. MEASSuRE addresses this weakness by reproducing the mechanical and electrical environment of cells in vivo in a controlled environment in vitro.