Physiological stretch of cells in vitro
Cells are stretched within their healthy limits.
Stem cells that differentiate into a specific tissue have properties that resemble adult tissue more closely when the cells are under mechanical and electrical stimulation during the differentiation process. MEASSuRE has the capability to provide both, electrical and mechanical stimulation.
Drug Toxicity Testing
Tissues grown from stem cells differentiated under mechanical and electrical stimulation are more representative of their respective organ in an adult human. Thus, the validity of drug toxicity testing by pharmaceutical company increases. MEASSuRE has the capability to provide both, electrical and mechanical stimulation.
There are a variety of mechanisms for transducing and sensing mechanical forces in neurons and other cell types. MEASSuRE provides capabilities to fundamentally understand the effect of mechanical forces.