MEASSuRE: 3 methods, 1 tool
Reproduces the electrical and mechanical environment of cells in the body. Using BMSEED’s proprietary stretchable microelectrode arrays (sMEAs), this tool combines electrophysiology, mechanical stretching, and imaging to produce more accurate, relevant data.
Stretchable MicroElectrode Array
Our stretchable MEAs are incorporated with the MEASSuRE system. They provide the only method for researchers to manipulate chemical, electrical, and mechanical factors independently to more closely replicate the complexity of the human body.
Accurate Data
Simulate the cell’s natural environment in the body to generate more relevant in vitro data.
Efficient Workflow
Concurrently apply multiple paradigms with MEASSuRE to save time, money, and research animals.
Unrivaled Results
Better predict clinical outcomes by eliminating drug candidates early & reduce failure rate in clinical trials.
What Our Customers Say
“Tuneable parameters and very fast to use.”
-Alyssa Pybus, Ph.D. Georgia Tech
“Easiness for acquiring electrical signal in a non-invasive manner.”
-Alex Patino, Ph.D. Arizona State University
“The most valuable thing is that we can record from cells multiple times…injure and record on the same device.”
-Mary Kate Dwyer, M.S. Columbia University
a) organotypic hippocampal slice cultures (OHSCs), long-term potentiation (LTD) & long-term depression (LTD) induced post-injury; b) primary hippocampal neurons (PHNs) & brain tissue tolerance to traumatic brain injury (TBI); c) organotypic spinal cord slice cultures (OSCSCs) & cypin regulated pain sensitivity after spinal cord injury (SCI); d) human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), hiPSC-CM differentiation; e) neurons, astrocytes, & microglia, pro-inflammatory signaling & immune response to mild traumatic brain injury (mTBI)
Publications
O. Graudejus, T. Li, J. Cheng, N. Keiper, R.D. Ponce Wong, A.B. Pak, J. Abbas
Applied Physics Letters, 2017, 110, 221906
Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury
W. H. Kang, W. Cao, O. Graudejus, T. Patel, S. Wagner, D. Meaney, B. Morrison III
Journal of Neurotrauma, 2015, 32(13), 1011-1019
Z. Yu, O. Graudejus, C. Tsay, S. P. Lacour, S. Wagner, B. Morrison
Journal of Neurotrauma, 2009, 26(7):1135-1145