MEA Electrophysiology
Cell Stretching
Imaging
All-in-One System
MultiElectrode Array Stretching Stimulating and Recording Equipment (MEASSuRE)
MEASSuRE is a fully integrated in vitro research platform that enables mechanical stretching of cells and tissues, live optical imaging, and multielectrode array (MEA) electrophysiology for recording and electrical stimulation—performed independently or simultaneously within a single system.
BMSEED offers three MEASSuRE models, each designed to integrate three essential experimental modalities into one platform:
A precision cell stretching device for applying controlled biomechanical stimuli
A high-performance electrophysiology data acquisition system for MEA recording and stimulation
A live-cell imaging system for real-time visualization and strain verification
This unique combination of mechanical, optical, and electrical capabilities is enabled by BMSEED’s proprietary stretchable multielectrode array (sMEA) technology, which allows seamless mechanical and electrical interfacing with cell and tissue cultures for physiologically relevant in vitro research.
MEASSuRE-Mini: Compact Stretchable MEA System for Physiological In Vitro Research
The MEASSuRE-Mini is a compact, fully integrated platform designed for researchers who want to combine physiological cell stretching, live imaging, and multielectrode array (MEA) electrophysiology in a space-efficient and cost-effective system.
Applications of MEASSuRE-Mini
MEASSuRE-Mini is optimized for physiological stretch applications, including:
Tissue engineering
Regenerative medicine
Organ-on-a-chip models
Mechanobiology research
Cell maturation and functional studies.
Key Benefits
Apply physiologically relevant mechanical stretch to reproduce the native cellular environment inside the body, promoting improved cell maturation, health, and function
Perform real-time, in-situ electrophysiology measurements using BMSEED’s stretchable multielectrode arrays (sMEAs) to assess cellular health, functional activity, and maturity
Use live optical or fluorescence imaging to visualize cells and cellular processes during mechanical stimulation
MEASSuRE-Mini integrates three modules
Mechanics Module (PN: 15-00000)
Controlled cell and tissue stretching
Strain rates up to 1 s⁻¹
Maximum strain up to 20%
Radial, linear, and custom strain profiles using the same instrument
Electromagnetic actuation provides friction free and user friendly cell stretching capability (no vacuum pumps)
Imaging Module (PN: 12-00000)
Optical or fluorescence imaging during stretching
Real-time visualization of cells and tissue morphology
Electrophysiology Module (PN: 11-00000)
Up to 128 channels for MEA recording and electrical stimulation
Compatible with stretchable MEA (sMEA) technology
Laboratory Compatibility
The MEASSuRE-Mini is designed for flexible deployment in common lab environments, including:
Incubators
Benchtop laboratory setups
Proven Performance
MEASSuRE systems are actively used by research professionals across multiple application fields, delivering validated, reproducible results in real-world experimental settings.
To explore the differences between MEASSuRE-Mini, MEASSuRE-Premium, and MEASSuRE-X, scroll down to view the comparison table or detailed technical specifications.
MEASSuRE-Premium: High-Performance Stretchable MEA System for In Vitro Injury Models
The MEASSuRE-Premium system is engineered for advanced pathological stretch and injury research, enabling researchers to reproduce high-strain, high-strain-rate mechanical trauma while simultaneously performing electrophysiology and live imaging in a controlled in vitro environment.
Applications of MEASSuRE-Premium
MEASSuRE-Premium is optimized for pathological stretch applications, including:
Traumatic brain injury (TBI) and repeated concussion models
Spinal cord injury (SCI)
Neurodegenerative disease research
Muscle injury and degeneration studies
Neuroprotection and therapeutic screening
Key Benefits
Apply pathological mechanical stretch to accurately reproduce the biomechanics of traumatic injuries, including TBI and SCI
Perform real-time electrophysiology measurements using BMSEED’s stretchable multielectrode arrays (sMEAs) to assess cellular health and function before and after injury
Evaluate the efficacy of neuroprotective compounds and therapeutic strategies using functional electrophysiological readouts
Use live optical or fluorescence imaging to visualize cells and tissue responses during mechanical deformation
MEASSuRE-Premium integrates three modules
Mechanics Module (PN: 14-00000)
Controlled mechanical stretching at strain rates up to 50 s⁻¹
Maximum strain up to 50%, enabling severe injury modeling
Imaging Module(PN: 12-00000)
Optical or fluorescence imaging during stretching
Real-time visualization of cellular morphology and injury response
Electrophysiology Module (PN: 11-00000)
Up to 128 channels for MEA recording and electrical stimulation
Compatible with stretchable MEA (sMEA) technology
Laboratory Compatibility
The MEASSuRE-Premium system is designed for benchtop laboratory environments, supporting flexible integration into existing experimental workflows.
Performance
MEASSuRE systems are trusted by research professionals across neuroscience and mechanobiology, delivering validated, reproducible results in demanding injury research applications.
To explore differences between MEASSuRE-Mini, MEASSuRE-Premium, and MEASSuRE-X, scroll down to view the MEASSuRE comparison table or detailed technical specifications.
MEASSuRE-X: Ultra-High-Speed Stretchable MEA System for Severe In Vitro Injury Models
MEASSuRE-X is BMSEED’s most advanced stretchable multielectrode array (sMEA) platform, designed for extreme pathological stretch and high-strain-rate injury research. It enables researchers to accurately reproduce rapid mechanical trauma while simultaneously performing electrophysiology and live imaging in a controlled in vitro environment.
Applications for MEASSuRE-X
MEASSuRE-X is optimized for high-strain, high-velocity pathological stretch applications, including:
Traumatic brain injury (TBI) and repeated concussion models
Spinal cord injury (SCI)
Neurodegenerative disease research
Muscle injury and degeneration studies
Neuroprotection and therapeutic screening
Key Benefits
Apply ultra-fast pathological mechanical stretch to replicate the biomechanics of severe traumatic injuries, including TBI and SCI
Perform real-time electrophysiological measurements using BMSEED’s stretchable multielectrode arrays (sMEAs) to quantify cellular health and functional changes before and after injury
Evaluate the protective effects of drug candidates and neuroprotective compounds using functional electrophysiology readouts
Use live optical or fluorescence imaging to visualize cellular deformation, injury progression, and recovery during mechanical stretch
MEASSuRE-X integrates three modules
Mechanics Module (PN: 13-00000)
Controlled stretching at strain rates up to 90 s⁻¹
Maximum strain up to 50%, enabling severe and rapid injury modeling
Imaging Module (PN: 12-00000)
Optical or fluorescence imaging during stretching
Real-time visualization of cellular and tissue responses
Electrophysiology Module (PN: 11-00000)
Up to 128 channels for MEA recording and electrical stimulation
Compatible with stretchable MEA (sMEA) technology
Laboratory Compatibility
The MEASSuRE-X platform is designed for benchtop laboratory environments, supporting flexible integration into advanced mechanobiology and injury research workflows.
Proven Performance
MEASSuRE platforms are actively used by research professionals across neuroscience and trauma research, delivering validated, reproducible results in demanding experimental applications.
To compare MEASSuRE-X with MEASSuRE-Mini and MEASSuRE-Premium, scroll down to view the MEASSuRE comparison table or detailed technical specifications.
Comparing MEASSuRE Models
MEASSuRE-Mini is designed for physiological stretch applications, and enables researchers to reproduce the normal mechanical environment of cells inside the body. It supports assessment of cell health, functional activity, and maturation using real-time electrophysiological measurements, with live imaging to visualize cells and cellular processes during mechanical stimulation.
MEASSuRE-Premium is optimized for pathological stretch models that replicate the biomechanics of traumatic injury, including traumatic brain injury (TBI) and spinal cord injury (SCI). The system enables pre- and post-injury electrophysiology analysis to assess cellular health and function, combined with optical or fluorescence imaging during stretch.
MEASSuRE-X is BMSEED’s highest-performance system, designed for very rapid pathological stretch and high-strain-rate injury models. It accurately reproduces the biomechanics of severe traumatic injuries such as TBI and SCI, while enabling real-time electrophysiological assessment of cellular function and live imaging throughout the stretching process.
MEASSuRE System FAQs
Can MEASSuRE be integrated with existing lab equipment?
Yes. MEASSuRE systems are designed for flexible integration with existing laboratory equipment, including electrophysiology and imaging setups. To confirm compatibility with your current instrumentation and workflows, contact BMSEED for a technical consultation.
Can MEASSuRE modules be purchased separately?
Yes. Each MEASSuRE platform consists of three core modules—Mechanics, Imaging, and Electrophysiology—which are also available as stand-alone tools. For example, laboratories that do not require live-cell imaging can combine the mechanical stretching module with the electrophysiology module to measure tissue response to stretch without optical imaging.
How much does a MEASSuRE system cost?
The price of a MEASSuRE system depends on the selected model (Mini, Premium, or X), the included modules (mechanics, imaging, electrophysiology), and their configuration. For accurate pricing and configuration options, contact BMSEED to request a quote.
What training and support are included with MEASSuRE?
BMSEED provides comprehensive onboarding and training with every MEASSuRE purchase. This includes in-person or virtual training sessions, along with detailed tutorial videos, documentation and user manuals, to ensure successful system setup and confident operation.
Mechanics
radial, uniaxial, and custom strain fields
one or a few very fast impulse stretches or continuous cyclical stretch
any stretch pattern
high reproducibility
product numbers (PNs): 13-00000 (X), 14-00000 (Premium), 15-00000 (Mini)
compare models using this technical datasheet
What cell and tissue types can be used with MEASSuRE?
MEASSuRE is compatible with a wide range of cell types and tissue cultures grown in vitro, making it suitable for diverse mechanobiology and electrophysiology applications. Customers have successfully used MEASSuRE with:
Primary hippocampal neurons
Organotypic hippocampal slice cultures
Organotypic spinal cord slice cultures
Neurons, astrocytes, and microglia
Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes
Cerebral organoids
Cardiac spheroids
This broad compatibility enables applications in neuroscience, cardiac research, organoid models, injury research, and regenerative medicine.
What safety features are included with the MEASSuRE system?
All MEASSuRE models include built-in safety features to support safe operation in research laboratories. Each system is equipped with two emergency stop buttons—one integrated into the electronics enclosure and a second external emergency stop that can be placed anywhere within the user’s workspace for immediate access.
Imaging
optical or fluorescence imaging before, during, and after stretching
cells remain in focal plane throughout stretching motion
up to 2,000 frames per second at 2MP resolution (optical)
configurable as needed
custom, easy-to-use software to independently measure the tissue strain
Product Number (PN): 12-00000
Is the live cell imaging system suitable for all types of biological tissues?
BMSEED’s MEASSuRE platform supports live-cell optical and fluorescence imaging during mechanical stretching, enabling real-time visualization of cellular and tissue responses. This includes applications such as verifying cell adhesion to the substrate, monitoring cell morphology, and measuring calcium ion (Ca²⁺) signaling dynamics during stretch.
Imaging requirements can vary depending on tissue type, thickness, and experimental goals. To determine the most suitable optical or fluorescence imaging configuration for your laboratory and biological model, contact BMSEED for a personalized consultation.
Electrophysiology
electrodes stretch with the cells/tissue
recording/stimulation before, during, and after stretching
comparison of pre- and post-stretch electrophysiological activity (normalization)
stretchable multielectrode arrays (MEAs) on elastomeric silicone substrates
standard MEAs on glass substrates also available
Product Number (PN): 11-00000
Does the data acquisition system support real-time data analysis?
Yes. The MEASSuRE electrophysiology module is powered by a data acquisition system that supports real-time electrophysiological data analysis and flexible data export for downstream processing.
Built-in analysis and visualization tools include:
Peri-Stimulus Time Histogram (PSTH) for stimulus-response analysis
Inter-Spike Interval (ISI) histograms to assess neuronal firing patterns
Spectrogram and spectrum analysis for frequency-domain evaluation
Spike Scope with user-selectable spike detection and artifact rejection thresholds
Electrophysiological data can be easily exported to MATLAB, spreadsheet formats, or image files, enabling seamless integration with existing data analysis workflows.