In Vitro Research Tools with True In Vivo Relevance
BMSEED bridges the gap between in vitro models and human physiology by uniquely integrating biomechanics and electrophysiology in advanced life science instrumentation.
MEASSuRE: Integrated Biomechanics and Electrophysiology in One Platform
MEASSuRE is an advanced in vitro research system that combines mechanical stretching of cells and tissues, real-time optical imaging, and multielectrode array (MEA) electrophysiology—independently or simultaneously—to deliver physiologically relevant data that better predicts in vivo behavior.
Stretchable MultiElectrode Array (sMEA)
Stretchable multielectrode arrays (sMEAs) are the core technology of the MEASSuRE platform, uniquely enabling independent control of chemical, electrical, and mechanical stimuli in in vitro experiments. BMSEED’s sMEAs more accurately replicate the biomechanical and electrophysiological complexity of human physiology, delivering physiologically relevant data that better predicts in vivo behavior.
What Our Customers Say
BMSEED’s MEASSuRE system provides precise mechanical and electrical control that enables highly reproducible, quantitative electrophysiology data.
“Easiness for acquiring electrical signal in a non-invasive manner.”
-A. Patino, Ph.D. Arizona State University
“The most valuable thing is that we can record from cells multiple times…injure and record on the same device.”
-M.K. Dwyer, M.S. Columbia University
“Tuneable parameters and very fast to use.”
-A. Pybus, Ph.D. Georgia Institute of Technology
a) organotypic hippocampal slice cultures (OHSCs), long-term potentiation (LTD) & long-term depression (LTD) induced post-injury; b) primary hippocampal neurons (PHNs) & brain tissue tolerance to traumatic brain injury (TBI); c) organotypic spinal cord slice cultures (OSCSCs) & cypin regulated pain sensitivity after spinal cord injury (SCI); d) human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), hiPSC-CM differentiation; e) neurons, astrocytes, & microglia, pro-inflammatory signaling & immune response to mild traumatic brain injury (mTBI)
Accurate Data
Simulate the cell’s natural environment in the body to generate more relevant in vitro data.
Efficient Workflow
Concurrently apply multiple paradigms with MEASSuRE to save time, money, and research animals.
Unrivaled Results
Better predict clinical outcomes by eliminating drug candidates early & reduce failure rate in clinical trials.
Latest Publications
M. K. Dwyer, I. Polsfuss, K. Herbert, N. Varghese, B. Morrison III
Biomedical Physics & Engineering Express, 2025, 11(2025)045029
M. K. Dwyer, N. Amelinez-Robles, I. Polsfuss, K. Herbert, C. Kim, N. Varghese, T. J. Parry, B. Buller, T. A. Verdoorn, C. B. Billing Jr, B. Morrison III
Experimental Neurology, 2024, 371, 114608
D. Sullivan, B. J. Vaglio, M. M. Cararo‑Lopes, R. D. Ponce Wong, O. Graudejus, B. L. Firestein
Annals of Biomedical Engineering, 2024, 52(4), 1021-1038
