In Vitro Research Tools with In Vivo Relevance
BMSEED bridges the gap between in vitro research and human physiology by combining biomechanics and electrophysiology in advanced life sciences instrumentation.
MEASSuRE: 3 methods, 1 tool
MEASSuRE is a complete solution for researchers to stretch cells/tissue mechanically, image them optically, and perform electrophysiological measurements, independently or concurrently.
Stretchable MultiElectrode Array
Stretchable multi-electrode arrays (sMEAs) are the core of the MEASSuRE system, uniquely enabling independent control of chemical, electrical, and mechanical stimuli to more accurately replicate the complexity of human physiology.
What Our Customers Say
Our systems deliver precise mechanical and electrical control for reproducible, quantifiable data, improving preclinical predictivity and advancing the translational power of in vitro research.
“Easiness for acquiring electrical signal in a non-invasive manner.”
-A. Patino, Ph.D. Arizona State University
“The most valuable thing is that we can record from cells multiple times…injure and record on the same device.”
-M.K. Dwyer, M.S. Columbia University
“Tuneable parameters and very fast to use.”
-A. Pybus, Ph.D. Georgia Institute of Technology
a) organotypic hippocampal slice cultures (OHSCs), long-term potentiation (LTD) & long-term depression (LTD) induced post-injury; b) primary hippocampal neurons (PHNs) & brain tissue tolerance to traumatic brain injury (TBI); c) organotypic spinal cord slice cultures (OSCSCs) & cypin regulated pain sensitivity after spinal cord injury (SCI); d) human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), hiPSC-CM differentiation; e) neurons, astrocytes, & microglia, pro-inflammatory signaling & immune response to mild traumatic brain injury (mTBI)
Accurate Data
Simulate the cell’s natural environment in the body to generate more relevant in vitro data.
Efficient Workflow
Concurrently apply multiple paradigms with MEASSuRE to save time, money, and research animals.
Unrivaled Results
Better predict clinical outcomes by eliminating drug candidates early & reduce failure rate in clinical trials.
Latest Publications
M. K. Dwyer, I. Polsfuss, K. Herbert, N. Varghese, B. Morrison III
Biomedical Physics & Engineering Express, 2025, 11(2025)045029
M. K. Dwyer, N. Amelinez-Robles, I. Polsfuss, K. Herbert, C. Kim, N. Varghese, T. J. Parry, B. Buller, T. A. Verdoorn, C. B. Billing Jr, B. Morrison III
Experimental Neurology, 2024, 371, 114608
Stretch‑Induced Injury Affects Cortical Neuronal Networks in a Time‑ and Severity‑Dependent Manner
D. Sullivan, B. J. Vaglio, M. M. Cararo‑Lopes, R. D. Ponce Wong, O. Graudejus, B. L. Firestein
Annals of Biomedical Engineering, 2024, 52(4), 1021-1038
