BMSEED Receives Patent for Soft & Stretchable Microelectrode Arrays with 3D Pocket and Microfluidic Channel
We’re proud to announce that BMSEED LLC has been awarded the following U.S. patent: Soft and Stretchable Microelectrode Arrays (sMEAs) with 3D Pocket and Microfluidic Channel (U.S. Patent No. US20240082843A1). Developed by Dr. Oliver Graudejus, Francisco Javier Lopez Arellano, Cami Caitlyn Rowan, and Dr. Ruben Dario Ponce Wong, this technology marks a major advance in the field of bioelectronic interfaces and organoid research.
Redefining the Interface Between Biology and Electronics
The newly patented system integrates a soft, stretchable microelectrode array with a three-dimensional pocket and built-in microfluidic channels. This design allows living organoids or tissue models to be cultured, stimulated, and monitored in a dynamic environment that closely mimics physiological conditions.
Unlike traditional rigid electrode systems, BMSEED’s sMEA platform is biomechanically compatible with soft biological tissues, enabling high-fidelity electrical recording and stimulation while maintaining cell health and structural integrity. The integrated microfluidics provide precise control of nutrient flow and chemical delivery, creating a responsive, tunable environment for real-time biological studies.
Transforming Organoid and Disease Modeling
This technology represents a significant leap forward in organoid-on-chip and in vitro disease modeling. By combining electrical and mechanical compatibility with fluidic control, the sMEA system enables researchers to:
Record electrophysiological signals from 3D organoids and engineered tissues
Deliver localized stimuli or compounds via integrated microfluidics
Simulate physiological motion and deformation in a controlled laboratory setting
These capabilities have far-reaching applications in neurological and cardiac research, drug discovery, and toxicology testing, providing more predictive and human-relevant data than ever before.
Continuing BMSEED’s Commitment to Bioelectronic Innovation
The approval of this patent — alongside BMSEED’s recently granted Peripheral Nerve Interface Device (US12343544B2) — reinforces our leadership in soft, stretchable bioelectronics designed to safely and seamlessly connect with living systems.
“Our goal is to create bioelectronic tools that enable deeper insight into how biological tissues communicate and respond to their environment,” said Dr. Oliver Graudejus, Co-Founder and CEO of BMSEED. “This sMEA platform allows researchers to study living tissues in ways that were previously impossible.”
Patent Information:
Title: Soft & Stretchable Microelectrode Arrays (sMEAs) with 3D Pocket and Microfluidic Channel
Inventors: Oliver Graudejus, Francisco Javier Lopez Arellano, Cami Caitlyn Rowan, Ruben Dario Ponce Wong
Assignee: BMSEED LLC
Patent No.: US20240082843A1
Together, these patented technologies underscore BMSEED’s mission to bridge the gap between biology and electronics — developing materials and devices that make the body and machines work as one.
Learn more about BMSEED’s innovations in soft bioelectronics at bmseed.com, or contact us directly to learn more.